![]() ![]() Our commitment to quality and consistency results in a reliable product that helps provide confidence in your research. No matter where in the world you are conducting your research, an IDT oligo is an IDT oligo. Our manufacturing processes result in high coupling efficiencies (Figure 1) and are standardized across our global manufacturing sites (Figure 2) to provide you with most consistent quality in the industry. The assays were evaluated via randomized protein variants within a protein scaffold topology and offer a method to remove the limitation of variant developability quantification. Our ability to control these variables allows us to consistently produce high-quality oligos for use in routine and specialized applications.Īn important measure of quality for any oligo manufacturer is coupling efficiency, because this directly affects the amount of full-length product you receive. Nearly every component of our manufacturing process is designed and developed in-house, including specialized synthesizers that can accommodate the most demanding oligo requests, and high-throughput automation systems that ensure fast turnaround times. IDT's long-standing reputation as a pioneer in custom oligo manufacturing is largely due to our vertically integrated proprietary synthesis platforms. ![]() *Guaranteed yield for unmodified oligos 25–50 bases will vary with oligo composition, length, and purification. * With the exception of mixed base oligos, which could potentially represent multiple sequences and therefore cannot be evaluated by ESI -MS.įor standard, desalted oligos ≥20 bases, we offer the following yield guarantees: Product In addition, your oligos will be quality controlled via proprietary ESI-MS *, and quantified twice by UV spectrophotometry to provide yield measurements. such as certain antibody fragments, scaffold proteins, peptides, and small molecules. Using the Oligo Entry ordering tool, you can design your oligos to containĪny DNA sequence you require and select from hundreds of modifications to suit your specific research needs.Įvery DNA Oligo you receive will be deprotected and desalted to remove small molecule impurities. More than 20 monoclonal antibodies are approved for therapy today. Target Capture Probe Design & Ordering ToolĭNA Oligonucleotides are short, single- and double-stranded synthetic DNA sequences that can be used in a variety of molecular biology applications.Library Concentration Conversion Calculator.Alt-R Predesigned Cas9 crRNA Selection Tool.develop the scaffold into an antibody mimetic with binding. SYBR Green dye assay and PrimeTime probe assays Antibody mimetics are proteins smaller than antibodies that have antigen-binding properties.PCR Allele Competitive Extension (PACE) genotyping.Drug target identification via CRISPR screening. ![]()
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